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however, HCV becomes chronic in 80 percent of those infected. ), a subendothelial cell-surface glycoprotein that binds phospholipid. The green dotted arrow represents a point of cross-over between the extrinsic and intrinsic pathways. The two pathways converge at the activation of factor X to Xa. Factor Xa has a role in the further activation of factor VII to VIIa as depicted by the green arrow. Active factor Xa hydrolyzes and activates prothrombin to thrombin. Thrombin can then activate factors XI, VIII and V furthering the cascade. Ultimately the role of thrombin is to convert fribrinogen to fibrin and to activate factor XIII to XIIIa. Factor XIIIa (also termed

Certainly, both styles still exist; certainly the particular mixture of links, commentary, and personal observation unique to each individual site has always given each weblog its distinctive voice and personality; and certainly the weblog has always been an infinitely malleable format. But the influx of blogs has changed the definition of weblog from "a list of links with commentary and personal asides" to "a website that is updated frequently, with new material posted at the top of the page." I really wish there were another term to describe the filter-style weblog, one that would easily distinguish it from the blog. On the principle of truth in advertising, this would make it much easier for the adventuresome reader to find the type of weblog he most enjoys.

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